Basic and clinical immunology – 3011. Evaluation of selected parameters of cellular immunity at diagnosis in children with osteosarcoma
نویسندگان
چکیده
Background Osteosarcoma is the most frequent primary malignant bone tumour, mainly affects children in the first and second decade of life. Causes of the disease are still unknown and reaction of the immune system on its development is very individual. Specific antigen-dependent cellular immunity plays an important role in this process. Cytotoxic T lymphocytes, NK , NKT and Tgδ lymphocytes are engaged directly in destruction of the tumour, helper T lymphocytes and indirectly B lymphocytes are of special importance. The aim of study was evaluation of selected elements of cellular immunity in children with osteosarcoma at diagnosis level.
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عنوان ژورنال:
دوره 6 شماره
صفحات -
تاریخ انتشار 2013